CD47 Antibody
Product Sizes
0.1 mg
OAEE00261-0.1MG
About this Product
- SKU:
- OAEE00261
- Additional Names:
- antigen identified by monoclonal antibody 1D8;antigenic surface determinant protein OA3;CD47 antigen (Rh-related antigen, integrin-associated signal transducer);CD47 glycoprotein;IAP;integrin associated protein;Integrin-associated protein;integrin-associated signal transducer;leukocyte surface antigen CD47;MER6;OA3;Protein MER6;Rh-related antigen.|CD47 molecule
- Application:
- Flow Cytometry, IHC-Frozen, Western Blot
- Buffer:
- TBS
- translate.label.attr.clone:
- MEM-122
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
- Formulation:
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- Host:
- Mouse
- Immunogen:
- COS-7 (African green monkey) cells
- Isotype:
- IgM
- Purity:
- >95%
- Purification:
- Purified
- Reactivities:
- Human, Non-human Primate, Porcine
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody MEM-122 reacts with CD47 (Integrin Associated Protein), a 50-55 kDa membrane adhesion molecule (thrombospondin receptor; immunoglobulin supergene family) expressed on leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. HLDA VI; WS Code AS A051
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php