Anti-HLA-DR [1D10 (Hu1D10; Apolizumab)]
Product Sizes
200 ug
AB03369-3-0-200UG
About this Product
- SKU:
- AB03369-3-0
- Additional Names:
- CD74; HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33
- Application:
- Flow Cytometry, Immunoprecipitation
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- 1D10 (Hu1D10; Apolizumab)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Mouse
- Immunogen:
- The original mouse antibody 1D10 was generated by immunizing female BALB/c mice intraperitoneally with human large cell lymphoma HO-85. Humanized version of this antibody was generated by grafting CDRs of the parental mouse antibody onto human framework regions.
- Isotype:
- IgG2b
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody recognizes a variant epitope on the beta chain of HLA-DR. It can bind some but not all HLA-DR beta chains. The antigen that this antibody binds is expressed on lymphocytes, macrophages, and dendritic (mesenchymal) cells and on most B cell neoplasms. HLA-DR is an MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. HLA-DR is
- Storage Conditions:
- 2-8[o]C Aliquot.
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03369-3.0