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Proteins and Peptides

FRP-4, soluble

Product Sizes
5ug
£178.82
S01-075S-5UG
About this Product
SKU:
S01-075S
Additional Names:
Secreted frizzled-related protein 4, DDC-4 (rat homologue)
translate.label.attr.clone:
(#9F40)
Extra Details:
HB-EGF is an EGF related growth factor that signals through the EGF receptor, and stimulates the proliferation of smooth muscle cells (SMC), fibroblasts, epithelial cells, and keratinocytes. HB-EGF is expressed in numerous cell types and tissues, including vascular endothelial cells and SMC, macrophages, skeletal muscle, keratinocytes, and certain tumor cells. The ability of HB-EGF to specifically bind heparin and heparin sulfate proteoglycans is distinct from other EGF-like molecules, and may be related to the enhanced mitogenic activity, relative to EGF, that HB-EGF exerts on smooth muscle cells. The human HB-EGF gene encodes a 208 amino acid transmembrane protein, which can be proteolytically cleaved to produce soluble HB-EGF. Recombinant human HB-EGF is a 9.7 kDa protein containing 86 amino acid residues, corresponding to the extra-cellular EGF-like and heparin binding domains of the full length HB-EGF protein.
Formulation:
lyophilized
Host:
Rat
Shipping Conditions:
Ambient
Storage Conditions:
Room Temperature
Supplier:
ReliaTech