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Proteins and Peptides

MIP-1 beta

Product Sizes
5ug
£178.82
R20-035S-5UG
About this Product
SKU:
R20-035S
Additional Names:
Ccl4; Scya4; Mip1-b
translate.label.attr.clone:
Rabbit IgG
Extra Details:
PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet alpha-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids).
Formulation:
lyophilized
Host:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
Room Temperature
Supplier:
ReliaTech