ABAT Polyclonal Antibody
Product Sizes
ABAT Polyclonal Antibody
RD83209A-120UL
About this Product
- SKU:
- RD83209A-120UL
- Additional Names:
- ABAT,GABA-AT,GABAT,NPD009
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
- Gene Details:
- ABAT
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human ABAT (NP_001120920.1).
- Isotype:
- IgG
- Protein Details:
- P80404
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 120 ul
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Synonyms:
- (S)-3-amino-2-methylpropionate transaminase;4-aminobutyrate aminotransferase, mitochondrial;4-aminobutyrate transaminase;GABA aminotransferase;GABA transaminase;GABA transferase;GABA-AT;GABAT;gamma-aminobutyrate aminotransferase;gamma-amino-N-butyrate transaminase;L-AIBAT;NPD009
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/24016/ABAT_Polyclonal_Antibody/