Recombinant mouse SDF-1/CXCL12 protein
Product Sizes
10ug
PAT-VH2TM5-10UG
20ug
PAT-VH2TM5-20UG
50ug
PAT-VH2TM5-50UG
100ug
PAT-VH2TM5-100UG
250ug
PAT-VH2TM5-250UG
About this Product
- SKU:
- PAT-VH2TM5
- Buffer:
- Liquid. In Phosphate Buffered Saline (pH7.4) containing 10% glycerol
- Extra Details:
- Cxcl12 also known as stromal cell-derived factor 1 isoform alpha. This protein acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. It stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. This protein inhibits CXCR4-mediated infection by T-cell line-adapted HIV-1. Cxcl12 protein plays a protective role after myocardial infarction. It induces down-regulation and internalization of ACKR3 expressed in various cells. Recombinant mouse Cxcl12, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
- Molecular Weight:
- 10.4 kDa (91aa) confirmed by MALDI-TOF
- Purity:
- >95%
- Sequence:
- KPVSLSY RCPCRFFESH IARANVKHLK ILNTPNCALQ IVARLKNNNR QVCIDPKLKW IQEYLEKALN K
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20°C or -80°C, 4°C
- Supplier:
- Nordic BioSite
- Manufacturer's Data Sheet:CXCL12 protein