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Antibodies

Anti-Hu CD129 Purified Low Endotoxin

Product Sizes
0.1 mg
AFC-RALR6M-0.1MG
About this Product
SKU:
AFC-RALR6M
Additional Names:
IL9R
Application:
ELISA, Flow Cytometry
Buffer:
Phosphate buffered saline (PBS), pH 7.4
translate.label.attr.clone:
AH9R7
Clonality:
monoclonal
Conjugate:
Unconjugated
Concentration:
1 mg/ml
Extra Details:
CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.
Format:
Purified Low Endotoxin
Immunogen:
Human CD129-transfected cell line
Isotype:
IgG2b k
Purity:
> 95% (by SDS-PAGE)
Purification:
Purified by protein-A affinity chromatography.
Research Area:
Cell Signaling
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody AH9R7 recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.
Storage Conditions:
Store at 2-8°C. Do not freeze.
Supplier:
Nordic BioSite