Anti-Hu CD263 Purified Azide Free
Product Sizes
0.1 mg
AFC-3OJ0YE-0.1MG
About this Product
- SKU:
- AFC-3OJ0YE
- Additional Names:
- TNFRSF10C, DcR1, TRAIL-R3, TRID, LIT
- Application:
- Flow Cytometry
- Buffer:
- Phosphate buffered saline (PBS), pH 7.4
- translate.label.attr.clone:
- TRAIL-R3-02
- Clonality:
- monoclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).
- Format:
- Purified Azide Free
- Immunogen:
- TRAIL-R3-hIgGhc fusion protein
- Isotype:
- IgG1
- Purity:
- > 95% (by SDS-PAGE)
- Purification:
- Purified by protein-A affinity chromatography.
- Research Area:
- Cell Death
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody TRAIL-R3-02 reacts with TRAIL-R3, a 35 kDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
- Storage Conditions:
- Store at 2-8°C. Do not freeze.
- Supplier:
- Nordic BioSite
- Manufacturer's Data Sheet:Anti-Hu CD263 Purified Azide Free