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Antibodies

Anti-Hu CD328 Purified

Product Sizes
0.1 mg
AFC-1B9L4X-0.1MG
About this Product
SKU:
AFC-1B9L4X
Additional Names:
SIGLEC7, p75/AIRM1, D-siglec
Application:
Flow Cytometry
Buffer:
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
translate.label.attr.clone:
6-434
Clonality:
monoclonal
Conjugate:
Unconjugated
Concentration:
1 mg/ml
Extra Details:
CD328, also known as Siglec-7 or p75/AIRM1, is a 75 kDa type I transmembrane glycoprotein of sialic acid-binding immunoglobulin-like lectin (Siglec) family. CD328 binds to sialylated glycans with alpha2,6 sialyl and alpha2,8 disyalyl residues and mediates sialic acid-dependent cell-cell binding. As it contains in its intracellular part the immunoreceptor tyrosine-based inhibitory motif (ITIM), it serves as an inhibitory receptor, e.g. of NK cells.
Format:
Purified
Immunogen:
human dendritic cells
Isotype:
IgG1
Purity:
> 95% (by SDS-PAGE)
Purification:
Purified by protein-A affinity chromatography.
Research Area:
Immunology
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody 6-434 recognizes an extracellular epitope of CD328 (Siglec-7), a 75 kDa transmembrane glycoprotein expressed mainly on NK cells, dendritic cells and monocytes.
Storage Conditions:
Store at 2-8°C. Do not freeze.
Supplier:
Nordic BioSite