Ac-DEVD-CHO Caspase 3 (Apopain) Inhibitor
Product Sizes
5 mg
ECH-864-20-5MG
About this Product
- SKU:
- ECH-864-20
- Extra Details:
- CAS Number: 184179-08-6Molecular Weight: 502.19Salt Form: N/APurity: >95%Sequence (3-letter): Ac-Asp-Glu-Val-Asp-CHOSequence (1-letter): Ac-DEVD-CHOStorage: -20 °C or belowSolubility: 13.7 mg/ml in DMSOCaspase-3 (Apopain) is commonly activated by numerous death signals and cleaves a variety of important cellular proteins and is essential for brain development. Ac-DEVD-CHO is a potent reversible inhibitor of caspase-3 (Ki < 1nM for purified caspase-3) and also inhibits caspase-7 (Ki = 1.6 nM) as well as other caspases to a lesser extent.References1. Talanian R.V. et al (1997) aoeSubstrate Specificities of Caspase Family Proteasesa 272 (15): 9677-9682.2. Godinat A. et al. (2013) aoeA Biocompatible in Vivo Ligation Reaction and Its Application for Noninvasive Bioluminescent Imaging of Protease Activity in Living Micea ACS Chemical Biology 8 (5): 987-999.
- Molecular Weight:
- 502.19
- Sequence:
- Ac-Asp-Glu-Val-Asp-CHO
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Echelon Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Manufacturer's Data Sheet:https://www.echelon-inc.com/product/ac-asp-glu-val-asp-cho-caspase-3-apopain-inhibitor/
