Mouse Endostatin ELISA Kit
Product Sizes
96 wells
£878.00
ARG81909-96WELLS
About this Product
- SKU:
- ARG81909
- Additional Names:
- KS; KNO; KNO1; Collagen alpha-1(XVIII) chain
- Application:
- ELISA
- CE/IVD:
- RUO
- Conjugate:
- HRP
- Extra Details:
- This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
- Physical State:
- Cell Culture Supernatant, Plasma, Serum
- Sensitivity:
- 78 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Assay Kits: ELISAs
