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Proteins and Peptides

Human FGFR3 recombinant protein (ECD) (Fc-His-tagged, C-ter)

Product Sizes
100 ug
£764.00
ARG70258-100UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG70258
Additional Names:
CEK2; CD antigen CD333; FGFR-3; ACH; JTK4; Fibroblast growth factor receptor 3; CD333; EC 2.7.10.1; HSFGFR3EX
Application:
Cell-based/Functional Assay, SDS-PAGE
Buffer:
PBS (pH 7.4)
CE/IVD:
RUO
Extra Details:
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. [provided by RefSeq, Aug 2017]
Purity:
>90%
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes