Human TrkA recombinant protein (Active) (ECD) (Fc-His-tagged, C-ter)
About this Product
- SKU:
- ARG70244
- Additional Names:
- TRK; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRKA; Tyrosine kinase receptor A; p140-TrkA; Trk-A; Tropomyosin-related kinase A; TRK1-transforming tyrosine kinase protein; TRK1; gp140trk; MTC; Tyrosine kinase receptor; EC 2.7.10.1
- Application:
- Cell-based/Functional Assay, SDS-PAGE
- Buffer:
- PBS (pH 7.4)
- CE/IVD:
- RUO
- Extra Details:
- This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
- Immunogen:
- TrkA (ECD)
- Purity:
- >97%
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:ARG70244.html
