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Antibodies

anti-CD152 / CTLA4 antibody [SQab22255]

Product Sizes
50 ul
ARG66927-50UL
100 ul
ARG66927-100UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG66927
Additional Names:
GRD4; CTLA-4; CELIAC3; CD; Cytotoxic T-lymphocyte-associated antigen 4; CD152; GSE; CD antigen CD152; Cytotoxic T-lymphocyte protein 4; ALPS5; IDDM12
Application:
IHC-Paraffin
Buffer:
PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA.
CE/IVD:
RUO
translate.label.attr.clone:
SQab22255
Clonality:
Monoclonal
Extra Details:
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
Host:
Rabbit
Immunogen:
Synthetic peptide within Human CTLA-4.
Isotype:
IgG
Purification:
Protein A Purified; Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Monoclonal Antibody