anti-ACVR1 / ALK2 antibody
Product Sizes
50 ug
ARG64410-50UG
100 ug
ARG64410-100UG
About this Product
- SKU:
- ARG64410
- Additional Names:
- ALK2; ACTRI; FOP; Serine/threonine-protein kinase receptor R1; Activin receptor type I; EC 2.7.11.30; Activin receptor-like kinase 2; TSRI; ACVRLK2; Activin receptor type-1; SKR1; ACVR1A; ACTR-I; TGF-B superfamily receptor type I; TSR-I; ALK-2
- Application:
- IHC-Paraffin, Western Blot
- Buffer:
- Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008]
- Host:
- Goat
- Immunogen:
- C-RKFKRRNQERLNPRD
- Isotype:
- IgG
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Reactivities:
- Canine, Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ARG64410.html
