anti-S6 Ribosomal Protein phospho (Ser240 / 244) antibody
About this Product
- SKU:
- ARG58169
- Additional Names:
- Phosphoprotein NP33; 40S ribosomal protein S6; S6
- Application:
- IHC-Paraffin, Immunoprecipitation, Western Blot
- Buffer:
- PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
- Host:
- Rabbit
- Immunogen:
- Phospho specific peptide corresponding to residues surrounding Ser240/244 of Human S6 Ribosomal Protein.
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ARG58169.html
