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Antibodies

anti-CREB phospho (Ser133) antibody

Product Sizes
50 ul
ARG52253-50UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG52253
Additional Names:
Cyclic AMP-responsive element-binding protein 1; CREB; CREB-1; cAMP-responsive element-binding protein 1
Application:
Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
CE/IVD:
RUO
Clonality:
Polyclonal
Extra Details:
CREB is a transcription factor. It is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Host:
Rabbit
Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser133 conjugated to KLH
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Amphibian, Avian, Bovine, Canine, Fish, Human, Mouse, Non-human Primate, Rat, Sheep
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Polyclonal Antibody
Immunofluorescence: Cultured Rat hippocampal slices stained with ARG52253 anti-CREB phospho (Ser133) antibody showing nuclear labeling of CREB phosphorylated at Ser133 in brown.
Western blot: a forskolin-stimulated Rat hippocampal slice showing phospho-specific immunolabeling of the ~45k CREB protein phosphorylated at Ser 133 stained with ARG52253 anti-CREB phospho (Ser133) antibody.