anti-CD284 / TLR4 antibody
About this Product
- SKU:
- ARG20469
- Additional Names:
- CD284; CD antigen CD284; ARMD10; hToll; TLR-4; TOLL; Toll-like receptor 4
- Application:
- Western Blot
- Buffer:
- PBS (pH 7.2), 30% Glycerol, 0.5% BSA and 0.01% Thimerosal
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- TLR4 (Toll-like receptor 4) is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide around 819 aa of Rat TLR4 protein (NP_062051.1)
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ARG20469.html
