Anti-CCR2 [MLN1202 (Plozalizumab, hu1D9)]
Product Sizes
100 ug
AB04182-3-3-100UG
About this Product
- SKU:
- AB04182-3-3
- Additional Names:
- CD192; C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; Monocyte chemoattractant protein 1 receptor; MCP-1-R; CMKBR2; MLN-1202; 4.9.2; LS132.1D9
- Application:
- Block/Inhibit/Neutralise, Flow Cytometry
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- MLN1202 (Plozalizumab, hu1D9)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Mouse
- Immunogen:
- The parental mouse antibody 1D9 was generated by immunizing mice with L1.2 transfectants expressing CCR2. The original humanized version of the antibody was generated by grafting CDRs of the mouse antibody 1D9 onto human framework regions.
- Isotype:
- IgG2b
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds and epitope between amino acids 1-30 in the amino terminal region of human CC-chemokine receptor 2. CCR2 receptor is a key functional receptor for CCL2, a chemokine which specifically mediates monocyte chemotaxis. CCL2 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. It can also bi
- Storage Conditions:
- 2-8[o]C Aliquot.
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab04182-3.3