AIM2 Polyclonal Antibody
Product Sizes
AIM2 Polyclonal Antibody
RD75605A-200UL
About this Product
- SKU:
- RD75605A-200UL
- Additional Names:
- Absent in melanoma 2,AIM 2,Aim2,AIM2,Interferon-inducible protein AIM2,OTTHUMP00000035296,PYHIN4
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS with 0.05% sodium azide and 50% glycerol, PH7.4
- Clonality:
- Polyclonal
- Concentration:
- 0.8 mg/ml
- Extra Details:
- Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN-, AIM2 is thought to act as a tumor suppressor by repressing NFB transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of -helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human AIM2
- Isotype:
- IgG
- Protein Details:
- O14862
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Size:
- 200 ul
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Synonyms:
- Absent in melanoma 2
- Manufacturer's Data Sheet:https://www.reddotbiotech.ca/antibodies/product/14986/AIM2_Polyclonal_Antibody/