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Antibodies

ALPL Polyclonal Antibody

Product Sizes
ALPL Polyclonal Antibody
RD70571A-200UL
Academic Pricing
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About this Product
SKU:
RD70571A-200UL
Additional Names:
AKP2,Alkaline phosphatase liver/bone/kidney,Alkaline phosphatase liver/bone/kidney isozyme,Alkaline phosphatase tissue nonspecific isozyme,Alkaline phosphatase,tissue-nonspecific isozyme,Alkaline phosphomonoesterase,Alpl,AP TNAP,AP-TNAP,APTNAP,BAP,FLJ40094,FLJ93059,Glycerophosphatase,HOPS,Liver/bone/kidney type alkaline phosphatase,MGC161443,MGC167935,PHOA,PPBT,Tissue non specific alkaline phosphatase,Tissue nonspecific ALP,TNAP,TNSALP
Application:
Western Blot
Buffer:
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Clonality:
Polyclonal
Concentration:
200 ug/ml
Extra Details:
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to Mouse Alkaline Phosphatase
Isotype:
IgG
Protein Details:
P05186, P08289, P09242
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Size:
200 ul
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody
Synonyms:
Alkaline phosphatase 2;Alkaline phosphatase liver/bone/kidney isozyme