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Antibodies

ASC / TMS1 Polyclonal Antibody

Product Sizes
ASC / TMS1 Polyclonal Antibody
RD266894A-200UL
Academic Pricing
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About this Product
SKU:
RD266894A-200UL
Additional Names:
PYCARD,ASC,CARD5,TMS,TMS-1,TMS1,PYD and CARD domain containing,ASC / TMS1
Application:
Immunofluorescence, Immunohistochemistry
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration:
1 mg/ml
Extra Details:
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant protein of human ASC / TMS1
Isotype:
IgG
Protein Details:
Q9ULZ3
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Size:
200 ul
Supplier:
Reddot
Type:
Antibody
Synonyms:
Caspase recruitment domain-containing protein 5;PYD and CARD domain-containing protein;Target of methylation-induced silencing 1