Anti-Human CD28 Monoclonal Antibody(AF488 Conjugated)
Product Sizes
Anti-Human CD28 Monoclonal Antibody(AF488 Conjugated)
RD22144F-20TESTS
About this Product
- SKU:
- RD22144F-20TESTS
- Additional Names:
- PAS2,MNS,HGpMiX,GYPA,GPSAT
- Application:
- Flow Cytometry
- Buffer:
- PBS with 0.05% Proclin300, 1% BSA
- translate.label.attr.clone:
- CD28.2
- Clonality:
- Monoclonal
- Conjugate:
- Alexa Fluor® 488
- Extra Details:
- CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
- Gene Details:
- CD28
- Host:
- Mouse
- Isotype:
- IgG1, kappa
- Protein Details:
- P10747
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Size:
- 20 tests
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Synonyms:
- T-cell-specific surface glycoprotein CD28;Tp44