Anti-Human CD47 Monoclonal Antibody(FITC Conjugated)
Product Sizes
Anti-Human CD47 Monoclonal Antibody(FITC Conjugated)
RD20774F-200TESTS
About this Product
- SKU:
- RD20774F-200TESTS
- Additional Names:
- Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP
- Application:
- Flow Cytometry
- Buffer:
- PBS with 0.05% Proclin300, 1% BSA
- translate.label.attr.clone:
- CC2C6D4
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Extra Details:
- CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with B Beta3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and B Beta3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.
- Gene Details:
- CD47
- Host:
- Mouse
- Isotype:
- IgG1, kappa
- Protein Details:
- Q08722
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Size:
- 200 tests
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Synonyms:
- antigen identified by monoclonal antibody 1D8;antigenic surface determinant protein OA3;CD47 antigen (Rh-related antigen, integrin-associated signal transducer);CD47 glycoprotein;IAP;integrin associated protein;Integrin-associated protein;integrin-associated signal transducer;leukocyte surface antigen CD47;MER6;OA3;Protein MER6;Rh-related antigen