Anti-Human CD45 Monoclonal Antibody(APC Conjugated)
Product Sizes
Anti-Human CD45 Monoclonal Antibody(APC Conjugated)
RD20584F-200TESTS
About this Product
- SKU:
- RD20584F-200TESTS
- Additional Names:
- Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45
- Application:
- Flow Cytometry
- Buffer:
- PBS with 0.05% Proclin300, 1% BSA
- translate.label.attr.clone:
- 9.4
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
- Gene Details:
- PTPRC
- Host:
- Mouse
- Isotype:
- IgG2a, kappa
- Protein Details:
- P08575
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Size:
- 200 tests
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Synonyms:
- B220;CD45;CD45 antigen;CD45R;GP180;LCA;L-CA;Leukocyte common antigen;LY5;protein tyrosine phosphatase, receptor type, c polypeptide;receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen