(NLysNpheNphe)2-NH2
About this Product
- SKU:
- PT-103
- Additional Names:
- (NLysNpheNphe)2-NH2, NLys-Nphe-Nphe-NLys-Nphe-Nphe-NH2, Peptoids, poly-N-substituted glycines, antibacterial, antiparasitic
- Extra Details:
- Peptoids are peptide-mimicking poly-N-substituted glycines, which exhibit enhanced physiological stability and are known to have antibacterial and antiparasitic qualities. They have recently been shown to have activity against Leishmania mexicana axenic amastigotes. NLys is the N-(4-aminobutyl)glycine peptoid monomer and Nphe is the N-(phenylmethyl)glycine peptoid monomer
- Immunogen:
- Antibacterials
- Molecular Weight:
- 862.1
- Physical State:
- Freeze dried solid
- Purity:
- >90%
- References:
- <p>Chongsiriwatana et al (2008) Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides. Proc. Natl. Acad. Sci <strong>105</strong>(8) 2794 DOI: 10.1073/pnas.0708254105 </p><p>Zuckermann (2011) Peptoid origins. Biopolymers, <strong>96</strong> 545 doi:10.1002/bip.21573 </p><p>Sun and Zuckermann (2013) Peptoid Polymers: A Highly Designable Bioinspired Material. ACS Nano <strong>7</strong>(6) 4715 https://doi.org/10.1021/nn4015714 </p><p>Huang et al (2014) Learning from Host-Defense Peptides: Cationic, Amphipathic Peptoids with Potent Anticancer Activity. PLoS ONE <strong>9</strong>(2) e90397. https://doi.org/10.1371/journal.pone.0090397 </p><p>Eggimann et al (2015) Investigating the Anti-leishmanial Effects of Linear Peptoids. ChemMedChem. <strong>10</strong> 233 doi:10.1002/cmdc.201402416</p>
- Sequence:
- NLys-Nphe-Nphe-NLys-Nphe-Nphe-NH2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in dilute acid
- Formula:
- C48H63N9O6