(Arg)9
About this Product
- SKU:
- AM-120
- Additional Names:
- Nonaarginine, Nona-L-arginine, Peptide R9
- CAS Number:
- 143413-47-2
- Extra Details:
- (Arg)9, also known as nonaarginine, is a a cationic cell penetrating peptide (CPP) consisting of 9 arginines. Arginine-rich cell-penetrating peptides including (arg)9 do not enter cells by directly passing through a lipid membrane but instead passively enter vesicles and live cells by inducing membrane multilamellarity and fusion. (Arg)9 also possesses antifungal and neuroprotective properties.
- Molecular Weight:
- 1423.7
- Purity:
- >95% by HPLC
- References:
- <p>Holm et al (2012) Cell-penetrating peptides as antifungals towards Malassezia sympodialis. Lett. Appl. Microbiol. <strong>54</strong> 39 <a href="https://pubmed.ncbi.nlm.nih.gov/22023266/" target="_blank" rel="nofollow">PMID: 22023266</a></p><p>Milani et al (2016) Poly-arginine peptides reduce infarct volume in a permanent middle cerebral artery rat stroke model. BMC Neurosci. <strong>17</strong>(1) 19 <a href="https://bmcneurosci.biomedcentral.com/articles/10.1186/s12868-016-0253-z" target="_blank" rel="nofollow">doi:10.1186/s12868-016-0253-z</a></p><p>Allolio et al (2018) Arginine-rich cell-penetrating peptides induce membrane multilamellarity and subsequently enter via formation of a fusion pore. Proc. Natl. Acad. Sci. <strong>115</strong> (47) 11923 <a href="https://pubmed.ncbi.nlm.nih.gov/30397112/" target="_blank" rel="nofollow">PMID: 30397112</a></p><p><a href="https://pubchem.ncbi.nlm.nih.gov/compound/Arg_9-TFA-salt" target="_blank" rel="nofollow">PubChem - (Arg)9</a><br></p>
- Sequence:
- H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store frozen and desiccated in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble in dilute acid
- Formula:
- C54H110N36O10