(+/-) RK-682
Product Sizes
200 ug
10-4300-200UG
1 mg
10-4300-1MG
About this Product
- SKU:
- 10-4300
- CAS Number:
- 154639-24-4
- Extra Details:
- RK-682 is a protein tyrosine phosphatase inhibitor (IC50's = 54 uM for CD45, 2.0 uM for VHR; did not inhibit cdc25B) originally isolated from the fermentation of Streptomyces sp. 88-682.1 Inhibits cell cycle at G1/S. RK-682 has also been shown to inhibit PLA2 (IC50 = 16 uM)2, HIV-1 protease (IC50 = 84 uM)3, and heparanase (IC50 = 17 uM)4. Natural RK-682 (R-isomer) and synthetic racemic material have identical phosphatase activity.5 Care should be taken when using RK-682 in the presence of metal salts - RK-682 readily forms metal complexes that affects its phosphatase inhibitory activity.6 RK-682 has been identified as a potential promiscuous inhibitor.7
- Immunogen:
- Phosphatase
- Molecular Weight:
- 368.52
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
