MS-275
Product Sizes
5 mg
10-2131-5MG
25 mg
10-2131-25MG
About this Product
- SKU:
- 10-2131
- Additional Names:
- Entinostat|SNDX-275
- CAS Number:
- 209783-80-2
- Extra Details:
- Potent HDAC inhibitor. Selective for HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 uM) and HDAC8 (IC50 > 100 uM).1 In vivo, MS-275 has been shown to inhibit tumor growth via induction of the tumor supressors p21WAF1/CIP1 and gelsolin2 and to block cell proliferation in a variety of cancer cell lines3,4. The compound has also shown significant anti-rheumatic activity in rat and mouse arthritis models.5
- Immunogen:
- Protein deacetylase
- Molecular Weight:
- 376.42
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
