AF/LE Purified Anti-Mouse CD115/CSF-1R Antibody[AFS98]
Product Sizes
25 ug
E-AB-F11070-25UG
100 ug
E-AB-F11070-100UG
1 mg
E-AB-F11070-1MG
50 ug
E-AB-F11070-50UG
5 mg
E-AB-F11070-5MG
500 ug
E-AB-F11070-500UG
25 mg
E-AB-F11070-25MG
50 mg
E-AB-F11070-50MG
100 mg
E-AB-F11070-100MG
About this Product
- SKU:
- E-AB-F11070
- Additional Names:
- Macrophage colony-stimulating factor 1 receptor;CSF-1 receptor (EC:2.7.10.1);CSF-1-R;CSF-1R;M-CSF-R;Proto-oncogene c-Fms;CD115;Csf1r;Csfmr;Fms
- Application:
- Block/Inhibit/Neutralise, Depletion, Flow Cytometry
- Buffer:
- Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
- translate.label.attr.clone:
- AFS98
- Clonality:
- Monoclonal
- Concentration:
- >= 1 mg/ml
- Extra Details:
- CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.
- Host:
- Rat
- Immunogen:
- CD115/CSF-1R
- Isotype:
- IgG2a, kappa
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:nDGCC0