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Assay Kits & ELISAs

Human CD274 / PD-L1 ELISA Kit

Product Sizes
96 wells
£878.00
ARG81929-96WELLS
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG81929
Additional Names:
Programmed cell death 1 ligand 1; B7-H1; B7H1; PDL1; PDCD1 ligand 1; B7 homolog 1; PD-L1; CD antigen CD274; PDCD1L1; B7-H; Programmed death ligand 1; PDCD1LG1
Application:
ELISA
CE/IVD:
RUO
Conjugate:
HRP
Extra Details:
CD274 / PD-L1 is an immune inhibitory receptor ligand. It is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Physical State:
Cell Culture Supernatant, Plasma, Serum
Sensitivity:
31.25 pg/ml
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C
Supplier:
Arigo Biolaboratories
Type:
Assay Kits: ELISAs