Anti-BCMA [17A5]
Product Sizes
1 mg
AB03124-3-3-BT-1MG
About this Product
- SKU:
- AB03124-3-3-BT
- Additional Names:
- CD269; BCM; TNFRSF17; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein
- Application:
- ELISA, Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- 17A5
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Human Fab format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- The original antibody was isolated from a generic Fab antibody library by panning against biotinylated ectodomain of BCMA.
- Isotype:
- IgG2b
- Purification:
- Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human and mouse BCMA. It acts as a receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. BCMA expression is highest on terminally differentiated B cells. BCMA is involved in mediating the survival of plasma cells for maintaining long-term humoral immunity. It also activates NF-kappa-B and JNK. The expression of BCMA has been linked to a number of cancers, autoimmune disorders, and
- Storage Conditions:
- 2-8[o]C
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03124-3.3-BT