Anti-CCL2 [CNTO 888 (Carlumab)]
Product Sizes
200 ug
AB02245-3-3-200UG
About this Product
- SKU:
- AB02245-3-3
- Additional Names:
- MCP-1; MCP1; HC11; MCAF; C-C motif chemokine 2; monocyte chemoattractant protein 1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; Monocyte secretory protein JE; Small-inducible cytokine A2
- Application:
- Block/Inhibit/Neutralise
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- CNTO 888 (Carlumab)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Mouse
- Immunogen:
- The original antibody was generated by phage display using the Human Combinatorial Antibody Library (HuCAL GOLD).
- Isotype:
- IgG2b
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody specifically binds human CCL2 and does not cross react with mouse CCL2 or other human CC chemokines. It is reported that CNTO 888 recognizes a conformational epitope encompassing residues 18-24 and 45-51 that overlaps the mapped receptor binding site.
- Storage Conditions:
- 2-8[o]C Aliquot.
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02245-3.3