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Antibodies

Anti-Tim-3 [2C12]

Product Sizes
100 ug
AB01057-1-32-100UG
About this Product
SKU:
AB01057-1-32
Additional Names:
CD366; HAVcr-2; HAVCR2; Hepatitis A virus cellular receptor 2 homolog; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; TIM-3; TIMD-3; TIM3; 8B.2C12
Application:
Block/Inhibit/Neutralise, Flow Cytometry, Immunofluorescence, Immunohistochemistry
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
2C12
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Mouse
Immunogen:
This antibody was raised by immunising rats with TIM-3:Ig fusion protein emulsified in complete Freund's adjuvant.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for murine TIM-3, a Th1-specific cell surface protein. TIM-3 is a type I transmembrane protein and contains an immunoglobulin and a mucin-like domain in its extracellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. This antibody binds to the BALB/c allele of TIM-3 while reactivity to the C57Bl/6 allele is significantly weaker.
Storage Conditions:
2-8[o]C Aliquot.
Type:
Antibody: Recombinant Antibodies