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Biotinylated Human CD30 / TNFRS8 Protein, Fc,Avitag[TM] (MALS verified)

Product Size(s)
25 ug
£382.00
CD0-H82F4-25UG
200 ug
£1582.00
CD0-H82F4-200UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
CD0-H82F4
Additional Names:
CD30|D1S166E|Ki-1|TNFRSF8
Buffer:
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Conjugate:
Biotin
Extra Details:
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
Molecular Weight:
66.6 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Epitope Tag:
AviTag™, Fc Tag
Long Description:
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
Accession:
NP_001234.2
Biotinylated Human CD30, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human CD30 Ligand, His Tag, low endotoxin (Cat. No. CDL-H524b) at 5 ug/mL (100 uL/well) can bind Biotinylated Human CD30, Fc,Avitag (Cat. No. CD0-H82F4) with a linear range of 0.6-20 ng/mL (QC tested).