Biotinylated Human CD30 / TNFRS8 Protein, Fc,Avitag[TM] (MALS verified) Citation Available Product Size(s) 25 ug £382.00 CD0-H82F4-25UG Add to order Added to order 200 ug £1582.00 CD0-H82F4-200UG Add to order Added to order Academic Pricing Please contact us for academic pricing. Contact Us About this Product SKU: CD0-H82F4 Additional Names: CD30|D1S166E|Ki-1|TNFRSF8 Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 Conjugate: Biotin Extra Details: Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Molecular Weight: 66.6 kDa Physical State: Powder Shipping Conditions: Ambient Storage Conditions: -20[o]C Supplier: ACRO Biosystems Type: Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein Epitope Tag: AviTag™, Fc Tag Long Description: Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Accession: NP_001234.2 Biotinylated Human CD30, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%. Immobilized Human CD30 Ligand, His Tag, low endotoxin (Cat. No. CDL-H524b) at 5 ug/mL (100 uL/well) can bind Biotinylated Human CD30, Fc,Avitag (Cat. No. CD0-H82F4) with a linear range of 0.6-20 ng/mL (QC tested). Need Help? View product citations for antibodies CD0-H82F4 on CiteAb