SPR-407
Gamma Synuclein Monomers
Cannot supply to this region.
- SKU:
- SPR-407
- Additional Names:
- Gamma-synuclein, Synuclein gamma, SNCG, SYUG_HUMAN, BCSG1, Breast cancer-specific gene 1, Persyn, PRSN, SR, Synoretin, Phosphoneuroprotein 14, PNP14, 14 kDa brain-specific
- Application:
- SDS-PAGE, WB, FuncS
- Concentration:
- 2 mg/ml
- Molecular Weight:
- 13.33 kDa
- Purity:
- >95%
- Purification:
- Ion Exchange
- Storage Conditions:
- -70[o]C
- Supplier:
- StressMarq Biosciences
- ABP:
- No Import Docs
- Buffer:
- PBS
- Immunogen:
- Gamma Synuclein Monomers
- Species:
- Human
- Uniprot:
- O76070
- Synonyms:
- -synuclein;BCSG1;breast cancer-specific gene 1 protein;E pound-synuclein;gamma-synuclein;persyn;SR;synoretin;synuclein, gamma (breast cancer-specific protein 1)
- Extra Details:
- Gamma-synuclein, encoded by the SNCG gene, is a member of the synuclein protein family, primarily expressed in the peripheral and central nervous systems. Unlike alpha-synuclein, which is extensively studied for its role in Parkinson's disease, gamma-synuclein monomers are emerging as critical modulators of neuronal architecture and signaling pathways. Functionally, gamma-synuclein contributes to the integrity of the neurofilament network and modulates axonal structure during development and adulthood. It activates key signaling cascades, including the MAPK and Elk-1 pathways, which are implicated in neuronal survival and plasticity. Recent findings suggest that gamma-synuclein may influence neurotransmitter secretion and synapse organization, positioning it as a potential player in neurodegenerative processes. In the context of neurodegeneration, gamma-synuclein's dysregulation has been associated with synaptic dysfunction and altered dopamine signaling-hallmarks of diseases such as Alzheimer's and Parkinson's. Its unique biochemical properties, including resistance to aggregation compared to alpha-synuclein, make gamma-synuclein monomers attractive candidates for biomarker development and therapeutic targeting. Ongoing research is exploring gamma-synuclein's interactions with other neurodegenerative proteins and its role in modulating cellular stress responses. As the field advances, gamma-synuclein monomers may offer new insights into disease mechanisms and open avenues for precision diagnostics and neuroprotective interventions.
- Shipping Conditions:
- Dry Ice