SPC-193
Cpn10 Antibody
Cannot supply to this region.
- SKU:
- SPC-193
- Additional Names:
- 10kDa Chaperonin, Chaperonin 10, Cpn 10, EPF, GROES, Heat Shock 10kD protein1, HSP10, HSPE1
- Application:
- ELISA, IHC, WB, IF, ICC, IP
- Concentration:
- 1 mg/ml
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Host:
- Rabbit
- Reactivities:
- Bovine, Canine, Human, Mouse, Porcine, Rabbit, Rat, Guinea Pig, Ovine
- ABP:
- IMP-GEN-2015-06 < 10% Serum <100ml
- Buffer:
- PBS pH7.3, 0.02% sodium azide
- Immunogen:
- Human Cpn10 peptide AA 91-101
- Uniprot:
- P61604
- Synonyms:
- 10 kDa chaperonin;10 kDa heat shock protein, mitochondrial;chaperonin 10;CPN10;early-pregnancy factor;EPF;epididymis secretory sperm binding protein;GROES;heat shock 10kD protein 1 (chaperonin 10);heat shock 10kDa protein 1;HSP10
- Extra Details:
- Cpn10 (Chaperonin 10), a member of the HSP10 family, functions as a co-chaperone with HSP60 to facilitate proper protein folding and assembly. It is essential for maintaining proteostasis, particularly under stress conditions such as oxidative damage and inflammation. In the nervous system, Cpn10 supports mitochondrial protein folding and cellular resilience. Its identification as early pregnancy factor and presence in serum suggest systemic regulatory roles, potentially acting as a stress-responsive signaling molecule. Given the central role of protein misfolding in neurodegenerative diseases like Alzheimer's and Parkinson's, Cpn10 is a candidate for therapeutic exploration in modulating chaperone networks and preventing proteotoxicity.
- Shipping Conditions:
- Blue Ice