RAB3D Antibody, Clone 5E9

Cannot supply to this region.

SKU:: SMC-614
Additional Names:: Member RAS Oncogene Family, D2-2, GOV, RAB16, RAD3D, Ras-Related Protein Rab-3D
Application:: WB
Concentration:: 1 mg/ml
Species Reactivity:: Human
Purification:: Protein G Purified
Storage Conditions:: -20[o]C
Supplier:: StressMarq Biosciences
Host:: Mouse
Reactivities:: Human, Mouse, Rat
ABP:: IMP-GEN-2015-06 < 10% Serum <100ml
Buffer:: PBS pH7.4, 50% glycerol, 0.09% sodium azide
Immunogen:: Full length recombinant Human RAB3D protein
Clone:: 5E9
Uniprot:: O95716
Synonyms:: D2-2;epididymis secretory sperm binding protein;glioblastoma overexpressed;GOV;RAB16;Rab3D upregulated with myeloid differentiation;RAD3D;ras-related protein Rab-3D
Extra Details:: RAB3D is a member of the Rab family of small GTPases involved in regulated exocytosis. It plays a role in vesicle trafficking from the trans-Golgi network and is essential for protein secretion in various cell types. Although best known for its function in osteoclast-mediated bone resorption, RAB3D is also expressed in the nervous system, where it may influence synaptic vesicle dynamics and neurotransmitter release. Given the importance of vesicle trafficking in neuronal communication, dysregulation of RAB3D could contribute to synaptic dysfunction in neurodegenerative diseases. Its role in exocytosis makes it a candidate for further investigation in disorders characterized by impaired synaptic transmission.