SMC-613D-APC
RAB1A, Clone 4G10: APC
Cannot supply to this region.
- SKU:
- SMC-613D-APC
- Additional Names:
- GTP binding protein RAB 1A, RAB 1, Rab 1A, Rab1A, RAB1A member RAS oncogene family, RAB1A_HUMAN, Ras related protein Rab 1A, Ras-related protein Rab-1A, YPT1-related protein, RAB1
- Application:
- WB, IP
- Concentration:
- 1 mg/ml
- Species Reactivity:
- Human
- Purification:
- Protein G Purified
- Storage Conditions:
- See Manual
- Supplier:
- StressMarq Biosciences
- Host:
- Mouse
- Reactivities:
- Human, Mouse
- ABP:
- IMP-GEN-2015-06 < 10% Serum <100ml
- Buffer:
- 95.46mM Phosphate, 2.48mM MES and 2mM EDTA
- Immunogen:
- Full length recombinant Human RAB1A protein
- Clone:
- 4G10
- Uniprot:
- P62820
- Synonyms:
- GTP binding protein Rab1a;Rab GTPase YPT1 homolog;RAB1;RAB1, member RAS oncogene family;ras-related protein Rab-1A;YPT1;YPT1-related protein
- Extra Details:
- RAB1A is a small GTPase localized to the membranes of the endoplasmic reticulum (ER) and Golgi apparatus. It regulates vesicular trafficking between these compartments and is essential for maintaining cellular homeostasis. In the nervous system, RAB1A supports the transport of proteins critical for synaptic function and neuronal survival. It has been implicated in the regulation of growth hormone secretion and intracellular signaling pathways. Dysfunction of RAB1A-mediated trafficking contributes to ER stress and impaired proteostasis-key features of neurodegenerative diseases such as Parkinson's and Alzheimer's. As a regulator of early secretory pathways, RAB1A is a potential target for modulating protein misfolding and aggregation in neurodegeneration.
- Shipping Conditions:
- Blue Ice