Corticosterone EIA Kit

Cannot supply to this region.

SKU:: SKT-205
Additional Names:: (11B Beta)-11,21-dihydroxypregn-4-ene-3,20-dione
Physical State:: Cell Culture Supernatant, Feces, Plasma, Serum, Urine
Storage Conditions:: 2-8[o]C, -20[o]C
Supplier:: StressMarq Biosciences
ABP:: No Import Docs
Immunogen:: Corticosterone EIA Kit
Format:: Colorimetric
Extra Details:: Corticosterone (C₂₁H₃₀O₄) is a glucocorticoid hormone secreted by the adrenal cortex in response to ACTH stimulation. It is the primary stress hormone in rodents and a precursor to aldosterone. In neuroscience research, corticosterone is widely used to model chronic stress and its effects on brain function. Elevated corticosterone levels have been shown to impair memory retrieval, alter sleep-wake cycles, and exacerbate neurodegenerative processes. In Parkinson's disease models, chronic corticosterone exposure increases alpha-synuclein phosphorylation and aggregation, particularly in the hypothalamus, and contributes to dopaminergic neuron loss. These findings highlight corticosterone's role in stress-induced neurotoxicity and its relevance in studying the pathophysiology of neurodegenerative and psychiatric disorders.