XIB4035

Cannot supply to this region.

SKU:: SIH-646
Additional Names:: (E)-N4-(7-chloro-2-(2-chlorostyryl)quinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine, 3(H3PO4)
Molecular Weight:: 750.4
Purity:: >98%
Source:: Synthetic
Storage Conditions:: -20[o]C
Supplier:: StressMarq Biosciences
CAS Number:: 10023-54-8
Extra Details:: XIB4035 is a small-molecule GFRA Alpha1 agonist and GDNF pathway modulator with neuroprotective and neuroregenerative activity. It activates RET signaling and promotes neurite outgrowth, mimicking key effects of the neurotrophic factor GDNF. The GDNF-GFRA Alpha1-RET pathway is highly relevant to neurodegeneration research. In a Parkinson's disease mouse model, RET was shown to be essential for the neuroprotective and neuroregenerative effects of GDNF, supporting the use of XIB4035 as a tool to study neuronal survival and repair mechanisms.