Pridopidine

Cannot supply to this region.

SKU:: SIH-626
Additional Names:: 4-(3-(Methylsulfonyl)phenyl)-1-propylpiperidine; ACR16
Molecular Weight:: 281.4
Purity:: >98%
Source:: Synthetic
Storage Conditions:: -20[o]C
Supplier:: StressMarq Biosciences
CAS Number:: 346688-38-8
Extra Details:: Pridopidine is a small molecule with neuroprotective potential, primarily investigated for Huntington's disease, Parkinson's disease, and schizophrenia. Initially described as a dopamine stabilizer due to its ability to modulate dopaminergic tone without inducing catalepsy, its mechanism is now attributed to high-affinity binding at the sigma-1 receptor. This receptor is implicated in cellular stress responses, neuroprotection, and synaptic plasticity. Pridopidine has demonstrated the ability to restore neuronal function, enhance neurotrophic signaling, and reduce neurodegeneration in preclinical models. Its sigma-1-mediated effects also extend to models of amyotrophic lateral sclerosis (ALS), highlighting its broad therapeutic potential in neurodegenerative disease research.