SIH-610
Urolithin A
Cannot supply to this region.
- SKU:
- SIH-610
- Additional Names:
- 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one; or 2',7-Dihydroxy-3,4-benzocoumarin
- Molecular Weight:
- 228.2
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 1143-70-0
- ABP:
- No Import Docs
- Extra Details:
- Urolithin A is a gut microbiota-derived metabolite of dietary ellagitannins, known for its ability to induce mitophagy and improve mitochondrial health. In neurodegenerative disease research, Urolithin A has demonstrated neuroprotective effects by promoting mitophagy and suppressing NLRP3 inflammasome activation in microglial cells. These mechanisms are particularly relevant in models of Parkinson's disease and Alzheimer's disease, where mitochondrial dysfunction and neuroinflammation are key pathological features. Urolithin A also enhances T cell function ex vivo, suggesting broader implications for immune modulation in neurodegenerative conditions.
- Shipping Conditions:
- Ambient