SIH-605
Aphidicolin
Cannot supply to this region.
- SKU:
- SIH-605
- Additional Names:
- (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol; (from Nigrospora sp.)
- Molecular Weight:
- 338.5
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 38966-21-1
- ABP:
- No Import Docs
- Extra Details:
- Aphidicolin is a specific inhibitor of DNA polymerase A Alpha and D Delta, arresting cells in early S phase without affecting other polymerases. It is widely used in cell cycle studies and apoptosis research. In neuroscience, Aphidicolin is employed to investigate DNA replication stress, cell cycle regulation, and gene amplification in neural cells, contributing to the understanding of neurodegenerative mechanisms involving genomic instability.
- Shipping Conditions:
- Ambient