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SIH-596

SGI-1027

Cannot supply to this region.

SKU:
SIH-596
Additional Names:
N-[4-[(2-Amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)benzamide
Molecular Weight:
461.5
Purity:
>98%
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
CAS Number:
1020149-73-8
ABP:
No Import Docs
Extra Details:
SGI-1027 is a small-molecule inhibitor of DNA methyltransferases (DNMTs), including DNMT1, DNMT3A, and DNMT3B. It interferes with epigenetic regulation by blocking DNA methylation, thereby reactivating silenced genes. In neurodegenerative disease research, SGI-1027 is of interest for its potential to modulate gene expression patterns associated with neuronal survival, synaptic plasticity, and neuroinflammation. Epigenetic dysregulation is a hallmark of several CNS disorders, and DNMT inhibitors like SGI-1027 may offer therapeutic avenues for restoring normal gene function.
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Ambient