SIH-591
Z-Guggulsterone
Cannot supply to this region.
- SKU:
- SIH-591
- Additional Names:
- (Z)-Pregna-4,17(20)-diene-3,16-dione
- Molecular Weight:
- 312.5
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 39025-23-5
- ABP:
- No Import Docs
- Extra Details:
- Z-Guggulsterone is a bioactive phytosteroid that functions as a selective antagonist of the farnesoid X receptor (FXR), inhibiting FXR transactivation and modulating bile acid signaling. It also acts as an inhibitor of the retinoic acid receptor (RAR) pathway. In neuroscience, Z-Guggulsterone has shown potential in attenuating astrocyte-mediated neuroinflammation by suppressing the toll-like receptor 4 (TLR4) pathway. This anti-inflammatory activity positions it as a candidate for further investigation in neurodegenerative disease models where glial activation and chronic inflammation are key pathological features.
- Shipping Conditions:
- Ambient