SIH-587
Baricitinib
Cannot supply to this region.
- SKU:
- SIH-587
- Additional Names:
- 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile, INCB028050, LY3009106
- Molecular Weight:
- 371.4
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 1187594-09-7
- ABP:
- No Import Docs
- Extra Details:
- Baricitinib is a selective Janus kinase (JAK1/JAK2) inhibitor that modulates immune signaling by suppressing cytokine release. While primarily used in autoimmune diseases and COVID-19-related cytokine storm management, Baricitinib is gaining interest in neuroinflammation research. Chronic activation of JAK-STAT signaling is implicated in neurodegenerative diseases such as multiple sclerosis and Alzheimer's. By dampening pro-inflammatory cytokine cascades, Baricitinib may offer neuroprotective benefits and is being explored as a therapeutic candidate for CNS disorders involving immune dysregulation and glial activation.
- Shipping Conditions:
- Ambient