SIH-584
Tafamidis
Cannot supply to this region.
- SKU:
- SIH-584
- Additional Names:
- 2-(3,5-Dichlorophenyl)-1,3-Benzoxazole-6-Carboxylic Acid, FX-1006, 2-(3,5-Dichlorophenyl)-6-benzoxazole carboxylic acid
- Molecular Weight:
- 308.1
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 594839-88-0
- ABP:
- No Import Docs
- Extra Details:
- Tafamidis is a pharmacological chaperone that stabilizes the tetrameric form of transthyretin (TTR), preventing its dissociation into monomers that can misfold and aggregate. While its primary clinical application is in delaying peripheral nerve damage in familial amyloid polyneuropathy (FAP), Tafamidis is increasingly recognized for its relevance in systemic amyloidosis research. Although not widely studied in neurodegenerative disease models, its mechanism-preventing amyloid fibril formation-parallels pathological processes in Alzheimer's and other protein misfolding disorders. Tafamidis serves as a model compound for exploring amyloid stabilization strategies and may inform future therapeutic approaches targeting neurodegenerative amyloidoses.
- Shipping Conditions:
- Ambient