SIH-565
Vismodegib
Cannot supply to this region.
- SKU:
- SIH-565
- Additional Names:
- Vismodegib; 879085-55-9; GDC-0449; Erivedge; 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide; HhAntag691
- Molecular Weight:
- 421.3
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 879085-55-9
- ABP:
- No Import Docs
- Extra Details:
- Vismodegib is a selective inhibitor of the Hedgehog signaling pathway via Smoothened (SMO) receptor antagonism. While primarily used in oncology, Vismodegib has emerging applications in neuroscience, particularly in studies of neural development, stem cell maintenance, and glioblastoma. Dysregulation of Hedgehog signaling has been implicated in neurodevelopmental disorders and brain tumors. Vismodegib is used to dissect the role of this pathway in neural stem cell proliferation, differentiation, and tumorigenesis.
- Shipping Conditions:
- Ambient