Zebularine

Cannot supply to this region.

SKU:: SIH-560
Additional Names:: 1H-B Beta-D-ribofuranosyl-2-pyrimidinone, NSC 309132, 1-(B Beta-D-Ribofuranosyl)-1,2-dihydropyrimidin-2-one, 2-Pyrimidone-1-B Beta-D-riboside, 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one, 4-deoxyuridine, NSC 309132, pyrimidin-2-one beta-D-ribofuranoside, pyrimidin-2-one beta-ribofuranoside, pyrimidin-2-one beta-ribofuranoside, (L)-isomer, pyrimidin-2-one ribonucleoside, zebularine, Pyrimidin-2-one ribonucleoside, Pyrimidin-2-one beta-ribofuranoside, Pyrimidin-2-one
Molecular Weight:: 228.2
Purity:: >98%
Source:: Synthetic
Storage Conditions:: -20[o]C
Supplier:: StressMarq Biosciences
CAS Number:: 3690-10-6
ABP:: No Import Docs
Extra Details:: Zebularine is a DNA methyltransferase (DNMT) inhibitor that induces DNA hypomethylation and reactivates silenced genes. In neurodegenerative disease research, Zebularine is used to explore the role of epigenetic modifications in neuronal plasticity, memory, and neuroinflammation. It is particularly relevant in studies of Alzheimer's disease, where aberrant DNA methylation contributes to gene silencing and synaptic dysfunction. Zebularine's stability and low toxicity make it a useful tool for investigating epigenetic therapies in the central nervous system.